Synthetic Biology in Cambridge

kings100b Research activities and studentship opportunities at the University of Cambridge. There is an index of research groups engaged in Synthetic Biology related work, with funding news and resources for people considering work in Cambridge. See a collection of web sites with extensive local information.

www.synbio.org.uk

Synbio news:

2 Oct 2010

Structural synthetic biotechnology: from molecular structure to predictable design for industrial strain development.

Structural synthetic biotechnology: from molecular structure to predictable design for industrial strain development.: "Publication Date: 2010 Oct PMID: 20727604
Authors: Chen, Z. - Wilmanns, M. - Zeng, A. P.
Journal: Trends Biotechnol

The future of industrial biotechnology requires efficient development of highly productive and robust strains of microorganisms. Present praxis of strain development cannot adequately fulfill this requirement, primarily owing to the inability to control reactions precisely at a molecular level, or to predict reliably the behavior of cells upon perturbation. Recent developments in two areas of biology are changing the situation rapidly: structural biology has revealed details about enzymes and associated bioreactions at an atomic level; and synthetic biology has provided tools to design and assemble precisely controllable modules for re-programming cellular metabolic circuitry. However, because of different emphases, to date, these two areas have developed separately. A linkage between them is desirable to harness their concerted potential. We therefore propose structural synthetic biotechnology as a new field in biotechnology, specifically for application to the development of industrial microbial strains.

(Via Trends in biotechnology.)

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