Synthetic Biology in Cambridge

kings100b Research activities and studentship opportunities at the University of Cambridge. There is an index of research groups engaged in Synthetic Biology related work, with funding news and resources for people considering work in Cambridge. See a collection of web sites with extensive local information.

www.synbio.org.uk

Synbio news:

25 Feb 2011

Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms.

Nat Rev Microbiol. 2011 Feb;9(2):131-7

Authors: Medema MH, Breitling R, Bovenberg R, Takano E

One of the most promising applications of synthetic biology is the biosynthesis of new drugs from secondary metabolites. Here, we survey a wide range of strategies that control the activity of biosynthetic modules in the cell in space and time, and illustrate how these strategies can be used to design efficient cellular synthetic production systems. Re-engineered versions of secondary metabolite biosynthetic pathways identified from any genomic sequence can then be inserted into these systems in a plug-and-play fashion.

PMID: 21189477 [PubMed - indexed for MEDLINE]

(Via pubmed: "synthetic biology".)

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