Compiled by Jim Haseloff at the University of Cambridge.
This site contains details of recent papers and activity in Synthetic Biology, with particular emphasis on: (i) development of standards in biology and DNA parts, (ii) microbial and (iii) plant systems, (iv) research and teaching in the field at the University of Cambridge, (v) hardware for scientific computing and instrumentation, (vi) tools for scientific productivity and collected miscellany.
Technology is driving revolutionary changes in biology. Over the past decade, scientists and engineers have begun to define the path forward in the genomic era. Systems Biology has arisen...
Now that we know the sequences of many genomes, from a wide variety of organisms and even from individuals with unique characteristics, many researchers have turned to making intentional...
The developments within synthetic biology promise to change the world in significant ways. Yet synthetic biology is largely unrecognized within conservation. The purpose of the meeting...
(Re-)constructing and Re-programming Life This conference will provide an in-depth discussion forum among practitioners of the various fields underlying Synthetic Biology. It aims to...
The BioBricks Foundation is pleased to announce The BioBricks Foundation Synthetic Biology 6.0 Conference (SB6.0), which will take place on July 9-11, 2013 at Imperial College, London,...
This course will focus on how the complexity of biological systems, combined with traditional engineering approaches, results in the emergence of new design principles for synthetic...
Biotechnol Adv. 2011 Jan-Feb;29(1):156-63
Authors: Wang X, Sa N, Tian PF, Tan TW
DNA assembly is one of the most fundamental techniques in synthetic biology. Efficient methods can turn traditional DNA cloning into time-saving and higher efficiency practice, which is a foundation to accomplish the dreams of synthetic biologists for devising cellular architectures, reprogramming cellular behaviors, or creating synthetic cells. In this review, typical strategies of DNA assembly are discussed with special emphasis on the assembly of long and multiple DNA fragments into intact plasmids or assembled compositions. Constructively, all reported strategies were categorized into in vivo and in vitro types, and protocols are presented in a functional and practice-oriented way in order to portray the general nature of DNA assembly applications. Significantly, a five-step blueprint is proposed for devising cell architectures that produce valuable chemicals.
PMID: 21034806 [PubMed - in process]
(Via pubmed: "synthetic biology".)