Cambridge website for Synthetic Biology Resources

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Compiled by Jim Haseloff at the University of Cambridge.

This site contains details of recent papers and activity in Synthetic Biology, with particular emphasis on: (i) development of standards in biology and DNA parts, (ii) microbial and (iii) plant systems, (iv) hardware for scientific computing and instrumentation, (v) tools for scientific productivity and (vi) collected miscellany.

The site also contains details of Synthetic Biology research and teaching at the University of Cambridge, including the annual iGEM team run by Jim Ajioka, Jim Haseloff and Gos Micklem in Cambridge.

 

www.synbio.org.uk

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SynBio calendar

  • 04 Jun

    Fourth International Workshop on Bio-Design Automation (IWBDA)

    The Fourth International Workshop on Bio-Design Automation (IWBDA) at DAC will bring together researchers from the synthetic biology, systems biology, and design automation communities....

  • 06 Jun

    New Phytologist Workshop: Synthetic Biology

    The overall goal for the workshop is to bring together scientists working in the highly interdisciplinary field of synthetic biology to present cutting-edge research aligned with three...

  • 20 Jun

    GCAT Synthetic Biology Workshop

    GCAT is pleased to announce a synthetic biology faculty workshop for the summer of 2012 (June 20-22) hosted by HHMI’s Science Education Alliance (SEA). The goal of this workshop...

  • 25 Jun

    enGENEious: Evolving Life for Future Technologies

    A student and post-doc organised conference: they have invited the world's leading scientists to highlight the recent advances in microbial engineering, along with discussing the challenges...

  • 30 Jul

    BioBuilding 2012 workshop

    A week long, professional development class will prepare educators to bring biological engineering and synthetic biology into their classrooms and laboratories. The workshop will include...

  • 24 Sep

    Synthetic Biology meeting in Cambridge, UK

  • 02 Nov

    iGEM2012 World Championship Jamboree

    Finals for the international Genetically Engineered Machine Competition.

  • 26 Nov

    CSH Asia Conference: Synthetic Biology

    The 2nd CSH Asia Synthetic Biology meeting will be held at the Suzhou Dushu Lake Conference Center in Suzhou, China, located approximately 60 miles west of Shanghai.

  • 09 Jun

    Gordon Conference: Synthetic Biology

    (Re-)constructing and Re-programming Life

04 Jun - 09 Jun
20 Jun - 27 Jun
30 Jul - 28 Sep
02 Nov - 01 Dec
09 Jun - 15 Jun

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RNAi patent jolt

 

RNAi patent jolt
Charlie Schmidt - Nature Biotechnology
 
28,
 
300
 
(2010)
 
doi:10.1038/nbt0410-300a, 

The US Patent and Trademark Office has issued a patent for detection of RNA-mediated gene silencing to Sir David Baulcombe, University of Cambridge, and Andrew Hamilton, University of Glasgow, over a decade after their gene silencing findings in plants were first reported (Science 286, 950–952, 1999). “The new patent has implications beyond plants,” says Jan Chojecki, CEO of Plant Bioscience Limited (PBL), of Norwich, the tech transfer company that owns the patents. “Anyone in the US profiling short RNAs and their impact on gene expression in mammalian systems is likely to be interested. We think it will create quite a stir.” The new patent recognizes Baulcombe and Hamilton's discovery that when genes are silenced complementary RNA strands of 20–30 bp accumulate—a finding that also proved critical to establishing short RNAs as a tool to manipulate gene expression. The initial patent for this technology, issued in 2004, was limited to plants, but the new patent broadens out to mammals. PBL expects to grant licenses to industry but will not enforce rights in academia, provided researchers use licensed detection kits. James McNamara, who directs the Office of Technology Management, University of Massachusetts Medical School, points out that Craig Mello and Andrew Fire, now at Stanford University, developed comparable RNA detection methods. “But if a company practices methods that might infringe on Baulcombe and Hamilton, they might take a license on it for reasonable terms,” he says.


From: http://www.nature.com/nbt/journal/v28/n4/full/nbt0410-300a.html

 

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Instrumentation

DNA parts

Plant systems

Productivity