- Synthetic Biology Faculty position
- SynBio2010 course in Synthetic Biology at Cambridge
- Synthetic Biology worth $4.5B by 2015
- Naked Scientist interview
- Royal Society: Future Technologies
- 2nd-generation GM traits
- NYT article about iGEM2009
- Synthetic Biology at the Wellcome Trust
- Giant Plant Cells
- Glass microbiology
- Endnote X3
- LEGO-sized hole punch
- Glowing Toyama Squid USB Memory Stick
- Green Pins
- Bacterial rainbow
- Synthetic operon for violacein production
- Cambridge team wins Grand Prize for iGEM2009
- The scatalog: E. chromi, pigment and poo
- Grand Prize for Cambridge iGEM2009 team
- Cambridge presentation at the iGEM2009 Jamboree
- Wellcome Trust iGEM2010 studentships
- Cambridge iGEM2009 team
- Synthetic Biology Project
- The iGEM Project
- RS Interface SynBio issue
- steam-powered dragon tin toy
- Magcloud: On Demand Magazine Printing
- RAE Synthetic Biology Report 2009
- Arduino Mega
- Phytocomp
- Computational Biology at Microsoft Research in Cambridge
- Open source hardware 2008
- www.synbio.org.uk news feeds
- Cambridge Network News
- iGEM 2008: Novice Bioengineers
- Plastic Logic e-Reader
- High Speed Photography using the Arduino
- Visitor's Guide to Cambridge
- Graduate Studies at Cambridge
- Emergence: a foundation for Synthetic Biology in Europe
- Bacillus Standards Working Group Meeting 1
- SynBioStandards UK Network in Synthetic Biology
- NumberKey turns your iPhone into a numeric Keypad
- Toast Bandages
- Soap Grenade
- Swiss Chocolate Knife
- Papercraft Turkey Dinner
- Miracle Fruit Tablets
- Wilting flower dies as your energy use blooms
- tikitag: RFID for the masses
- Predatory bacterial swarm uses rippling motion to reach prey
- Leonard et al Engineering microbes
- CatCam
- KAUST-Cambridge AEA
- iGEM2008 Jamboree
- Optical microscopy techniques for plants
- Computer modeling of plant morphogenesis
- Image Analysis of Cells
- Teaching materials from the University of Cambridge
- Scientific Computing in Cambridge
- Cheaposcope
- Gallery of Plant Images
- BioBrick vectors for Bacillus subtilis
- Tools for Arabidopsis
- Coleocheate as a model system
- Superfolder GFP
- IET Synthetic Biology
- Synthetic Biology in Plants
- Plant Visions exhibition
- iGEM2008 overview
- iGEM2009 studentships
- iGEM competition
- MIT Parts Registry
- An automated home-built low-cost fermenter suitable for large-scale bacterial expression of proteins in Escherichia coli.
- 90 billion tons of microbial organisms live in the deep biosphere
- Tesla 10 series
- The impact of online publishing
- The Moore's Law of microbiology - towards bacterial culture miniaturization with the micro-Petri chip.
- Moo does full-size business cards
- Handpresso - Portable Precise Espresso On the Go or at Home
- Book Darts
- Pinwheel and old VCR used to make wind-powered LED
- Firewinder LED windmill, for the eco-friendly barbershop
Engineering tools for Gram positive bacteria
Gram positive bacteria like Bacillus subtilis provide a number of benefits for synthetic biologists. B. subtilis is non-tranformable and naturally transformable, with an efficient system for homologous transformation. Gram positive bacteria provide the bulk of industrially important species and their architectures allow high level secretion of enzymes and other proteins. The Synthetic Biology group at the University of Cambridge is developing tools for work with B. subtilis. The pages in this section provide access to recent papers and relevant websites in the field.
90 billion tons of microbial organisms live in the deep biosphere
Biogeoscientists show evidence of 90 billion tons of microbial organisms-expressed in terms of carbon mass-living in the deep biosphere, in a research article published online by Nature, July 20, 2008. This tonnage corresponds to about one-tenth of the amount of carbon stored globally in tropical rainforests. The authors: Kai-Uwe Hinrichs and Julius Lipp of the Center for Marine Environmental Sciences (MARUM) at University of Bremen, Germany; and Fumio Inagaki and Yuki Morono of the Kochi Institute for Core Sample Research at the Japan Agency for Marine-Earth Science and Technology (JAMSTEC) concluded that about 87 percent of the deep biosphere consists of Archaea. This finding is in stark contrast to previous reports, which suggest that Bacteria dominate the subseafloor ecosystem. To reach this conclusion, the researchers investigated sediment cores collected from several hundred meters beneath the seafloor of the Atlantic and Pacific Oceans and the Black Sea. The cored sediments included samples that were the result of research expeditions conducted by the Integrated Ocean Drilling Program (IODP).
Bacterial culture miniaturization with the micro-Petri chip.
A recent publication has reported the fabrication of a new microbial culture device containing an array of unprecedented density - a million growth chambers. This micro-Petri chip should impact on various fields, including biotechnology, ecology, food microbiology and drug development, by enabling high-throughput screens and therefore the detection of rare phenotypes within a large population of microorganisms.
Publication Date: 2008 Jul PMID: 18453020
Authors: Gefen, O. - Balaban, N. Q.
Journal: Trends Biotechnol
Engineering microbes with synthetic biology frameworks.
Authors: Leonard, E. - Nielsen, D. - Solomon, K. - Prather, K. J.
Journal: Trends Biotechnol
Predatory bacterial swarm uses rippling motion to reach prey
Image shows swarm of M. xanthus bacteria (left) invading a colony of prey bacteria (right). The rippling pattern is the highly organized behavior of thousands of M. xanthus cells working in concert to digest the prey. Credit: John Kirby, University of Iowa Carver College of Medicine Like something from a horror movie, the swarm of bacteria ripples purposefully toward their prey, devours it and moves on.
First Bacillus Standards Working Group Meeting
Friday 16 January 2009
a SynBioStandards Network event
School of Computing Science University of Newcastle
A one-day workshop in Newcastle in January 2009, to bring together researchers interested in developing standards for using B. subtilis - a major new interest in the UK Synthetic Biology community, due to the potential benefits of the systems for homologous recombination, genomic assembly, protein secretion, biosafety, etc.
Microbes Menu
Microbe news
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Biogenic Insecticides Biogenic Insecticides Decoded ScienceDaily (Mar. 6, 2010) — In the latest issue of Science, researchers from the University of Freiburg report on their discovery of a new mode of action of insecticidal toxins from Photorhabdus...
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Microbial diversity in pitcher plants Vast Microbial Diversity of Carnivorous Pitcher Plant Uncovered enlarge Sarracenia alata flowers. (Credit: Photo by Noah Elhardt / Courtesy of Wikimedia Commons) From ScienceDaily (Mar. 29, 2010) — The microbial ecosystem...
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Microbes breathe life into oxygen theory From: http://www.cbc.ca/technology/story/2010/03/25/tech-bacteria-create-oxygen.html A new study of methane-munching microbes adds weight to the idea that bacteria were producing oxygen on Earth before photosynthesis evolved. Margaret Butler...
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Oceans' smallest lifeforms Census offers glimpse of oceans' smallest lifeforms ...
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Microbe networking Microbes May Be More Networked Than You Are (Wired Op-ed) When we think of networks, we think of humans and the cables we’ve run around the world to connect our species. Figuring out how to move electrons has transformed human society,...
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DIY molecular genetics supplies Bio Hacking Resources From: http://www.kk.org/cooltools/archives/000582.php I've been expecting tools for basement bio hacks any day now for about 20 years. They are getting real close, although most of what you can do with this stuff...
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Scientists visualize how bacteria talk to one another Using imaging mass spectrometry, researchers at the University of California, San Diego have developed tools that will enable scientists to visualize how different cell populations of cells communicate. Their study shows how bacteria talk to one...
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Bacillus Genome Stock Center news New acquisitions at the Bacillus Genome Stock Center Extract from: http://www.bgsc.org/NewThisMonth.htm (Aug 2009) New strains of B. subtilis A collaboration from groups at University of Maryland School of Medicine (J. Ravel...
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