Microbiology News
1. I Spy Researchers testing the ability of engineered E. colicells to stabilize unstable proteins in vivo, stumbled upon a new protein chaperone called Spy that suppresses protein aggregation and aids protein refolding. Spy is shaped unlike any other previously studied chaperone and can increase the steady-state levels of a set of unstable protein mutants up to 700-fold. S. Quan et al.,...
Diatomists shell out on nanotechnology It's unlikely that many nanotechnologists are familiar with diatoms - a group of single-celled shelled algae - but that could change following a world-first conference on diatom nanotechnology that's set to take place in the US in October. Liz Kalaugher spoke to conference organizer Richard Gordon of the University of Manitoba, Canada, to find out more....
The Colors Of Microbiology: Bacteria, Fungi & More By evad // August 26, 2008 11 comments From: http://www.colourlovers.com/blog/2008/08/26/the-colors-of-microbiology-bacteria-fungi/ The color of micro-organisms (fungi, bacteria, algae, and such) is due to different colored substances in the cells. For instance, bacteria use variants of chlorophyll (the green in...
Self-organization, layered structure, and aggregation enhance persistence of a synthetic biofilm consortium.: PLoS One. 2011;6(2):e16791 Authors: Brenner K, Arnold FH Microbial consortia constitute a majority of the earth's biomass, but little is known about how these cooperating communities persist despite competition among community members. Theory suggests that non-random spatial...
Biotechnol J. 2010 Dec;5(12):1277-96 Authors: Fischbach M, Voigt CA Bacteria construct elaborate nanostructures, obtain nutrients and energy from diverse sources, synthesize complex molecules, and implement signal processing to react to their environment. These complex phenotypes require the coordinated action of multiple genes, which are often encoded in a contiguous region of the genome,...
Biomaterials. 2011 Apr;32(10):2500-7 Authors: Choi WS, Ha D, Park S, Kim T We utilized a commercially available materials printer to investigate synthetic multicellular cell-to-cell communication because inkjet printing technology makes it easy to print spatiotemporal patterns of soluble biomolecules and live cells. Since cells are genetically programmed to communicate with one another via...
Bacteria are widely used to manufacture proteins used in medicine and industry, but the bugs often bungle the job. Many proteins fall apart and get cut up inside the bacteria before they can be harvested. Others collapse into useless tangles instead of folding properly, as they must in order to function normally. A research team led by James Bardwell, who is a professor of molecular, cellular...
Genomic comparison of ocean microbes reveals East-West divide in populations: Much as an anthropologist can study populations of people to learn about their physical attributes, their environs and social structures, some marine microbiologists read the genome of microbes to glean information about the microbes themselves, their environments and lifestyles. Using a relatively new methodology...
In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides.: "Publication Date: 2010 Oct 4 PMID: 20921390 Authors: Fraune, S. - Augustin, R. - Anton-Erxleben, F. - Wittlieb, J. - Gelhaus, C. - Klimovich, V. B. - Samoilovich, M. P. - Bosch, T. C. Journal: Proc Natl Acad Sci U S A Early embryos of many organisms develop outside the mother...
A team of Yale University scientists has engineered the cell wall of the Staphylococcus aureus bacteria, tricking it into incorporating foreign small molecules and embedding them within the cell wall. The finding, described online in the journal ACS Chemical Biology this week, represents the first time scientists have engineered the cell wall of a pathogenic "Gram-positive"...
Genome sequence of the solvent-producing bacterium Clostridium carboxidivorans strain P7T.: "Publication Date: 2010 Oct PMID: 20729368 Authors: Paul, D. - Austin, F. W. - Arick, T. - Bridges, S. M. - Burgess, S. C. - Dandass, Y. S. - Lawrence, M. L. Journal: J Bacteriol Clostridium carboxidivorans strain P7(T) is a strictly anaerobic acetogenic bacterium that produces acetate, ethanol, butanol,...
The unique binding mode of cellulosomal CBM4 from Clostridium thermocellum cellobiohydrolase A.: "Publication Date: 2010 Sep 17 PMID: 20654622 Authors: Alahuhta, M. - Xu, Q. - Bomble, Y. J. - Brunecky, R. - Adney, W. S. - Ding, S. Y. - Himmel, M. E. - Lunin, V. V. Journal: J Mol Biol The crystal structure of the carbohydrate-binding module (CBM) 4 Ig fused domain from the cellulosomal cellulase...
Imaging mass spectrometry of intraspecies metabolic exchange revealed the cannibalistic factors of Bacillus subtilis.: "Publication Date: 2010 Sep 14 PMID: 20805502 Authors: Liu, W. T. - Yang, Y. L. - Xu, Y. - Lamsa, A. - Haste, N. M. - Yang, J. Y. - Ng, J. - Gonzalez, D. - Ellermeier, C. D. - Straight, P. D. - Pevzner, P. A. - Pogliano, J. - Nizet, V. - Pogliano, K. - Dorrestein, P. C. Journal:...
Biogenic Insecticides Decoded ScienceDaily (Mar. 6, 2010) — In the latest issue of Science, researchers from the University of Freiburg report on their discovery of a new mode of action of insecticidal toxins from Photorhabdus luminescens, a bacterium which lives in a symbiotic relationship with nematodes. Galleria mellonella (greater wax moth) infected with Photorhabdus...
Vast Microbial Diversity of Carnivorous Pitcher Plant Uncovered enlarge Sarracenia alata flowers. (Credit: Photo by Noah Elhardt / Courtesy of Wikimedia Commons) From ScienceDaily (Mar. 29, 2010) — The microbial ecosystem inside the carnivorous pitcher plant is vastly more diverse than previously thought, according to research published in the March 2010 issue of the...
From: http://www.cbc.ca/technology/story/2010/03/25/tech-bacteria-create-oxygen.html A new study of methane-munching microbes adds weight to the idea that bacteria were producing oxygen on Earth before photosynthesis evolved. Margaret Butler of the Australian Institute for Bioengineering and Nanotechnology at the University of Queensland, and colleagues, report their study of a new kind...
Census offers glimpse of oceans' smallest lifeforms By Mark Kinver (http://news.bbc.co.uk/1/hi/sci/tech/8622608.stm) Science and...
Microbes May Be More Networked Than You Are (Wired Op-ed) When we think of networks, we think of humans and the cables we’ve run around the world to connect our species. Figuring out how to move electrons has transformed human society, but we are not the only species on earth that lives in a wired world. From the Fields is a periodic Wired Science op-ed series presenting...
Bio Hacking Resources From: http://www.kk.org/cooltools/archives/000582.php I've been expecting tools for basement bio hacks any day now for about 20 years. They are getting real close, although most of what you can do with this stuff so far is elementary, trivial and not very useful. Still, here are a few do-it-yourself gene hacking resources finally emerging. The prime users are...
Using imaging mass spectrometry, researchers at the University of California, San Diego have developed tools that will enable scientists to visualize how different cell populations of cells communicate. Their study shows how bacteria talk to one another – an understanding that may lead to new therapeutic discoveries for diseases ranging from cancer to diabetes and allergies. In the paper...

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