Cambridge website for Synthetic Biology resources

www.synbio.org.uk

Compiled by Jim Haseloff at the University of Cambridge. SpannerPlantLogo140This site contains details of recent papers and activity in Synthetic Biology, with particular emphasis on: (i) development of standards in biology and DNA parts, (ii) microbial and (iii) plant systems, (iv) research and teaching in the field at the University of Cambridge, (v) hardware for scientific computing and instrumentation, (vi) tools for scientific productivity and collected miscellany.

Similar to the Cambridge-based Raspberry Pi and OpenLabTools initiatives, we promote the use of low cost and open source tools - in our case for use in biological engineering.

Google: Synthetic Biology news

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Meetings: Synthetic Biology

  • 14 Sep 2014
    01:00 to 01:00

    This year's conference theme Systems Biology: The Fifth Element seeks to capture the multiple facets that comprise a systems understanding of life, as a single common thread that unifies seemingly different

14 Sep 19 Sep

Weather: Cambridge

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www.synbio.org.uk

DeviceEditor visual biological CAD canvas.

J Biol Eng. 2012 Feb 28;6(1):1

Authors: Chen J, Densmore D, Ham TS, Keasling JD, Hillson NJ

Abstract
ABSTRACT: BACKGROUND: Biological Computer Aided Design (bioCAD) assists the de novo design and selection of existing genetic components to achieve a desired biological activity, as part of an integrated design-build-test cycle. To meet the emerging needs of Synthetic Biology, bioCAD tools must address the increasing prevalence of combinatorial library design, design rule specification, and scar-less multi-part DNA assembly. RESULTS: We report the development and deployment of web-based bioCAD software, DeviceEditor, which provides a graphical design environment that mimics the intuitive visual whiteboard design process practiced in biological laboratories. The key innovations of DeviceEditor include visual combinatorial library design, direct integration with scar-less multi-part DNA assembly design automation, and a graphical user interface for the creation and modification of design specification rules. We demonstrate how biological designs are rendered on the DeviceEditor canvas, and we present effective visualizations of genetic component ordering and combinatorial variations within complex designs. CONCLUSIONS: DeviceEditor liberates researchers from DNA base-pair manipulation, and enables users to create successful prototypes using standardized, functional, and visual abstractions. Open and documented software interfaces support further integration of DeviceEditor with other bioCAD tools and software platforms. DeviceEditor saves researcher time and institutional resources through correct-by-construction design, the automation of tedious tasks, design reuse, and the minimization of DNA assembly costs.

PMID: 22373390 [PubMed - as supplied by publisher]

DeviceEditor visual biological CAD canvas.

 

(Via pubmed: "synthetic biology".)

Research news at Cambridge University

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www.marchantia.org

Online resources, including bibliography, weblinks and posters, for work with the simple plant system, Marchantia polymorpha.

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OpenLabTools: open technology in Cambridge

OpenMicroscope1

The OpenLabTools Project is a new initiative for the development of low cost and open access scientific tools at the University of Cambridge. With support from the Raspberry Pi Foundation, student projects include data acquisition, sensing, actuating, processing and 3D manufacturing, see the openlabtools.org website.

Research Studies

PhD Studentships in Cambridge

The Board of Graduate Studies manages admission of the University's graduate students. Prospective students should start here - for an introduction to the University of Cambridge, the courses we offer, how to apply for postgraduate study, how your application will be processed, and immigration and other important information.

Click here for more information about Cambridge