A transcription activator-like effector toolbox for genome engineering

A transcription activator-like effector toolbox for genome engineering: "

A transcription activator-like effector toolbox for genome engineering

Nature Protocols 7, 171 (2012). doi:10.1038/nprot.2011.431

Authors: Neville E Sanjana, Le Cong, Yang Zhou, Margaret M Cunniff, Guoping Feng & Feng Zhang

Transcription activator-like effectors (TALEs) are a class of naturally occurring DNA-binding proteins found in the plant pathogen Xanthomonas sp. The DNA-binding domain of each TALE consists of tandem 34–amino acid repeat modules that can be rearranged according to a simple cipher to target new

(Via Nature Protocols.)